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How To Check For Protein In Urine At Home

Proteinuria is the presence of too much protein in the urine. It is typically a sign of kidney affliction but tin occur with other medical conditions.

One of the master signs of proteinuria is foamy urine. Nonetheless, healthy people can experience foamy urine, and it can develop with conditions besides kidney disease.

In many people, proteinuria volition take no symptoms. If researched farther, nigh cases will not be linked to an underlying cause. Therefore, it may be an incidental finding or a more definitive cause may be identified if other symptoms are nowadays.

protein urine dipstick

A urine dipstick test is key to the diagnosis of proteinuria.

blueshot / Getty Images

This article looks at the symptoms of underlying conditions associated with protein in the urine, causes of poly peptide in the urine, and how proteinuria is diagnosed and treated. It also explains when to see a healthcare provider if you suspect yous take proteinuria or any conditions that cause it.

Symptoms of Proteinuria

Under normal circumstances, in that location is very little protein in your urine. The kidneys take a very skillful filtration barrier that prevents most proteins from leaving the claret, and those that exercise brand it through are but reabsorbed dorsum into apportionment.

Different mechanisms can permit protein to escape into the urine, including fifty-fifty transient proteinuria due to posture changes called postural proteinuria.

Foamy Urine As a Sign of Proteinuria

While foamy or frothy urine can exist a sign of proteinuria, other factors can cause urine to be foamy on occasion. The foaminess should be persistent over time earlier considering other causes, like decreased kidney function.

Foamy urine is not diagnostic of proteinuria. In fact, some people may have bilirubinuria (excess bilirubin in the urine) or retrograde ejaculation (the backflow of semen into the float).

If the kidneys accept sustained merely balmy damage, proteinuria may exist minimal to moderate, depending upon where in the kidney the damage has occurred. On the other hand, if the loss of kidney office is astringent, proteinuria may be a contributor to nephrotic syndrome in which fluids and dyslipidemia (unhealthy levels of cholesterol or fats) nowadays a more serious condition.

Symptoms of nephrotic syndrome include:

  • Foamy urine
  • Swelling of the hands and feet
  • Puffiness around the eyes, specially in the morning
  • The buildup of fluids in the abdomen
  • Shortness of jiff
  • Fatigue or tiredness

Causes of Proteinuria

Kidney disease is usually the first condition a healthcare provider will explore when in that location is backlog protein in the urine. But other conditions can cause proteinuria, some of which occur independently of kidney disease.

Kidney Disease

Proteinuria is a common feature of kidney illness. It is typically caused by harm to the tiny clusters of claret vessels that act as filters in the kidneys, called glomeruli. When these filters are damaged, more poly peptide tin escape into the urine.

The causes of this are many and are collectively referred to as glomerular disease.

Proteinuria tin also be caused by damage to tiny structures called proximal tubules that render protein to the bloodstream. When these units are damaged, there is nowhere for the excess protein to become just out of the torso in urine.

Proteinuria is mutual with the ii master types of kidney disease:

  • Acute kidney injury (AKI): This is the sudden decline in kidney infection due to dehydration, low blood pressure, stupor, congestive center failure (the heart cannot pump enough blood for the body'south needs), claret or fluid loss, and other causes.
  • Chronic kidney disease (CKD): This is progressive loss of kidney function, mainly due to loftier claret pressure, diabetes, glomerular disease, and polycystic kidney disease (a genetic affliction that causes clusters of cysts in the kidneys).

Other conditions that affect the kidney tin pb to proteinuria and include:

  • Fanconi's syndrome: A genetic disorder that tin damage proximal tubules
  • Goodpasture syndrome: An autoimmune disease affecting the lungs and kidneys
  • Granulomatosis with polyangiitis: An autoimmune disease that causes the inflammation of blood vessels throughout the torso
  • Lupus: An autoimmune disease that affects multiple organs
  • Preeclampsia: A pregnancy complication characterized past high claret pressure
  • Renal cell carcinoma: The near common type of kidney cancer

Overflow Proteinuria

Overflow proteinuria is when the amount of low molecular weight proteins in the blood exceeds the corporeality the kidneys can filter. When this happens, the excess protein exits the body in urine.

Certain weather condition tin can crusade overproduction of proteins that, in turn, leads to overflow proteinuria:

  • Multiple myeloma: A rare type of blood cancer that tin lead to an excessive accumulation of proteins called light chains
  • Rhabdomyolysis: The abnormal breakdown of muscle tissues that can lead to the buildup of proteins called myoglobulins

Medications

There are certain medications that can crusade proteinuria. These drugs are classified as nephrotoxic considering they are toxic to the kidneys.

Some nephrotoxic drugs can impairment the tubules and glomeruli of the kidneys as well as the tissues in between. Others cause the formation of crystals that block tubules, while others all the same cause the breakdown of musculus fibers (rhabdomyolysis) that triggers the overproduction of poly peptide.

The form of drugs unremarkably associated with nephrotoxicity are:

  • Antibiotics: Used to treat bacterial infections
  • Angiotensin-receptor blockers (ARBs): Used to treat high blood pressure
  • Chemotherapy drugs: Used to treat cancer
  • Illicit drugs: Including heroin, methadone, methamphetamine
  • Nonsteroidal anti-inflammatory drugs (NSAIDs): Used to reduce inflammation and pain
  • Rifampin: Used to treat tuberculosis

How to Care for Proteinuria

Proteinuria is not a disease merely rather a condition caused past some other illness. As such, the treatment is mainly focused on resolving or managing the underlying cause.

For instance, the symptoms of astute kidney injury—formerly known as acute kidney failure—will usually clear once the underlying condition is treated. In nearly cases, the kidney function will return to normal with no permanent damage to the kidneys.

With chronic kidney illness (CKD), the focus is placed on improving the function of the kidneys to tedious the progression of the disease. With respect to proteinuria, lifestyle measures (such as diet, exercise, and weight loss) volition help control diabetes and high claret force per unit area as means to tiresome progression of the illness.

In improver, medications similar ACE inhibitors and angiotensin II receptor blockers help reduce urine protein levels. Statin drugs, used to reduce cholesterol, appear to have similar benefits in people with CKD.

Are There Tests to Diagnose the Cause of Proteinuria?

Proteinuria itself tin can be diagnosed with a simple dipstick test. This involves dipping a specially treated paper strip into a sample of urine. Results are returned inside ane to two minutes.

To mensurate the exact corporeality of poly peptide excreted in the urine, your healthcare provider may recommend a 24-60 minutes urine collection examination. By evaluating the limerick of urine collected over 24 hours (including different types of proteins and waste material products), the lab can summate how much poly peptide is passed each day.

At-Home Testing of Proteinuria

Urine dipstick tests are commonly performed in a healthcare provider'south office, but at that place are at-home and mail-in tests that you lot can use in the privacy of your ain domicile.

Still, the urine dipstick will miss some special types of proteins (immunoglobulin), can result in trace protein in those with otherwise normal health, and a variety of atmospheric condition tin falsely lower or elevate the poly peptide reading.

There may be different things that interfere with mail-in tests. Consult your healthcare provider if you lot take other symptoms or accept doubts about how yous are interpreting the test.

While these tests can tell you whether or non yous have proteinuria, they cannot tell you what caused it if yous do. For this, yous would need to see a healthcare provider.

To make up one's mind the cause of proteinuria, the healthcare provider may order one or several of the following tests:

  • Blood tests: The comprehensive metabolic panel includes kidney function tests and glucose. This checks how well your kidneys are filtering blood a waste matter product called creatinine. Also, glucose is determined and followed upwards for uncontrolled diabetes, if appropriate. A hemoglobin A1c test also checks for glucose command.
  • Urinalysis: This is a urine test that can measure out levels of a type of protein chosen albumin, characteristically seen in people with proteinuria. It tin can also cheque for signs of infection (based on the presence of white claret cells) or evidence of bleeding.
  • Blood force per unit area: Checks to see if you have low claret pressure.
  • Toxicology test: Can cheque blood or urine for the presence of nephrotoxic substances, including illicit drugs.
  • Special imaging tests: These could include ultrasound (uses audio waves), computed tomography (CT) (creates three-dimensional X-ray images), or magnetic resonance imaging (MRI) (uses magnetic and radio waves).
  • Kidney biopsy: This involves the insertion of a long, hollow needle through the wall of the abdomen to obtain a sample of kidney tissue. The anatomic pathologist tin can then evaluate the sample to check for signs of infection, necrosis (tissue death), cancer, or other abnormalities.

When to See a Healthcare Provider

It can be difficult to know when it'south time to run across a healthcare provider nigh proteinuria because the symptoms are oftentimes so vague (and occasionally not-existent). Fifty-fifty if you take foamy urine, you might figure that it was "something you ate" if yous are otherwise feeling healthy.

And, that tin be a trouble. Because not only is proteinuria an indication that yous may take kidney disease, information technology is often a sign that kidney disease is advancing and condign more serious.

To this end, yous need to seek immediate medical intendance if you experience the following:

  • Gradually diminishing urine output
  • Swelling of the legs, ankles, or feet
  • Extreme tiredness or weakness
  • Shortness of breath
  • Nausea or airsickness
  • Chest pain or pressure
  • Irregular heartbeat

These are common signs of kidney failure, a condition in which the kidney function has dropped so severely that you may require hospitalization to avert illness or decease.

This is especially true if the symptoms develop over the bridge of several hours or days. Without handling, kidney failure is associated with a high take chances of death.

Summary

Proteinuria is the presence of excess presence of protein in the urine. It commonly occurs in people with kidney disease when the filters of the kidneys, called the glomeruli, are damaged. But, there are other causes as well, including drugs that are toxic to the kidneys and medical atmospheric condition that cause the excess production of protein in the body.

Proteinuria tin can be diagnosed with a simple urine dipstick test. The underlying cause may require claret and urine tests, imaging tests like ultrasound, and a kidney biopsy to pinpoint the cause.

The handling of proteinuria varies past the underlying crusade. If chronic kidney disease (CKD) is involved, exercise, changes in nutrition, weight loss, and medications may aid deadening the progression of the disease and assist alleviate proteinuria.

A Give-and-take From Verywell

The trouble with kidney disease is yous oft don't know you lot have it until the damage is done. According to the Center for Disease Control and Prevention (CDC), ii of every 5 adults living with severe kidney disease don't realize they have it.

If you lot suspect y'all have a kidney problem—or accept a family history of kidney disease—don't ignore the signs and symptoms. Go checked out today.

Frequently Asked Questions

  • How is protein in urine diagnosed?

    A urine dipstick test tin tell if at that place is protein in your urine, only it can't tell you lot how much. For this, you would need a 24-hour urine collection in which yous collect urine from the moment yous wake upwards in the morning time and every time thereafter until your outset pee the next morning. The lab can and then summate how much poly peptide is passed each twenty-four hour period based on the composition of your urine.

  • How much poly peptide in urine is too much?

    Nearly people pass less than 80 milligrams (mg) of protein in their urine each day. Values under 150 mg are considered normal. Proteinuria is diagnosed when urine protein levels are between 1 and xx grams (i,000 and 20,000 mg) per solar day, depending on the cause.

  • Tin you reverse proteinuria by cut out protein?

    Non really. Diet does non treat proteinuria. In the end, proteinuria is non an illness but a sign of an affliction. Equally such, you need to treat the underlying condition to improve proteinuria.

  • Are there other causes of proteinuria besides kidney disease?

    Yes, some may have no illness at all, every bit is the case in postural proteinuria or in those with dehydration.

    Just in that location are also many serious weather condition that can lead to permanent kidney damage. These include autoimmune diseases, genetic disorders, medications, certain cancers, and medical conditions that crusade overflow proteinuria (excess protein in the urine due to the overproduction of protein).

Source: https://www.verywellhealth.com/protein-in-urine-5223896

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